From the developer of the ColorVisor iOS app, an audio based game for both blind and sighted was recently released. The game is called, MouseKick, and is 0.99 in the App store.
There is a Youtube demonstration one can access
For information for MouseKick in the App Store,
The game, according to the developer, is fully VoiceOver compatible. There are different sounds for the mice and there is a training mode to get the user accustom to the game sounds and play.